Strategically located along the prime stretch of Orchard Road between ION Orchard and Ngee Ann City, Wisma Atria enjoys more than 100 metres of prime street frontage and has an established following among locals and tourists. The mall enjoys high pedestrian flow given its Orchard Road frontage and an underground pedestrian linkway which connects Wisma Atria to Orchard MRT Station and Ngee Ann City.

Wisma Atria is home to the flagship stores of international retailers including COACH, Emperor Watch & Jewellery and Mauboussin. The mall houses the first Tory Burch boutique in Singapore, the largest TAG Heuer boutique worldwide and a globally-recognised Swiss luxury watch retailer Rado. Its mid-to-upscale positioning also attracted fashion brands such as Cotton On Kids, Lacoste and Seafolly, local labels such as Charles & Keith and Pedro, as well as a wide range of beauty stores including the city's largest ETUDE HOUSE.

Shoppers can also look forward to differentiated tenant mix and experiential retail at Wisma Atria with the opening of new stores such as Singapore's leading sneaker boutique Limited EDT Chamber, Japan bridal rings boutique Venus Tears, prescription glasses boutique Lenskart and fashion accessories store Afterall. The opening of the Paradise Dynasty's flagship restaurant at Wisma Atria brings with it an expanded Food & Beverage offering, with dishes created exclusively for the outlet, amongst a myriad of other F&B options at the mall. Premium Korean fast food restaurant Burger+ presents a new dining concept and promises to wow patrons with its gourmet fusion burgers paired with beer or wine. Other food and beverage tenants at Wisma Atria include The Coffee Bean & Tea Leaf, Saveur, artisanal dessert cafe Bakerzin and a new concept store IRVINS Messy Kitchen by IRVINS Salted Egg which is popular among tourists. In FY 2018/19, the mall attracted a shopper traffic of 22.4 million.

The Wisma Atria office tower offers its tenants a prestigious Orchard Road address and amenities such as restaurants, gyms, healthcare providers and convenience shops within walking distance.